siRNA

siRNA

History

The story of siTOOLs Biotech

 



siTOOLs Biotech, co-founded by Dr. Michael Hannus and Prof. Gunter Meister in September 2013, is a spin-out of Intana Bioscience in Munich and the University of Regensburg, Germany.

Initially from Cenix Bioscience, one of the first RNA interference (RNAi) service companies, Michael gained many years of hands-on experience in RNAi screening and validation from its earliest days. Seeing off-target effects dominate results with conventional RNAi reagents, Michael decided to test the concept of complex but defined siRNA pools (siPOOLs) to "dilute" off- target effects and increase knock down specificity.

Supported by Intana Bioscience and the German EXIST program, Michael joined forces with Gunter Meister, a pioneer in RNAi biochemistry, to develop siPOOLs from proof-of-concept to a commercial product that entered the market beginning of 2014.
Since then, siTOOLs Biotech has provided reagents to a growing number of researchers from both academia and industry within Europe, US and Asia. Working from Munich Martinsried's dynamic biotech cluster, siTOOLs Biotech applies its proprietary technology with the aim of having RNAi to live up to its full potential and early promises – as an extremely versatile, fast and cost-effective method to study gene function in a broad range of experimental setups.

In Dec 2015, siTOOLs Biotech launched another product, raPOOLs, that provides specific and robust enrichment of RNA for interaction analysis. Following a similar pooling approach but towards pulldown applications, raPOOLs provide robust RNA enrichment at affordable costs.

siTOOLs Biotech continues to strive towards equipping the modern day scientist with tools for easy, specific and robust analysis of gene function.
 

 



Contact us to get the most out of your gene function studies.


  • Negative control siPOOLs
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    siTOOLs Biotech

    Negative control siPOOLs

    $266.00 - $803.00
    neg. control siPOOL 5 - 5 nmol negative control siPOOL neg. control siPOOL 10 - 10 nmol negative control siPOOL neg. control siPOOL 10 - 10 nmol negative control siPOOL neg. control siPOOL has been designed to have no significant...
    $266.00 - $803.00
  • pos. control siPOOL
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    siTOOLs Biotech

    pos. control siPOOL

    $266.00 - $803.00
    pos. control siPOOL 5 - 5 nmol positive control siPOOL pos. control siPOOL 10 - 10 nmol positive control siPOOL pos. control siPOOL 20 - 20 nmol positive control siPOOL Pos. control siPOOLs are pre-validated siPOOLs that...
    $266.00 - $803.00
  • raPOOL
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    siTOOLs Biotech

    raPOOL

    $428.00
    1 raPOOL / target   10 nmol raPOOL, pool of 30 biotinylated single-stranded DNA probes for enrichment of target RNA. Column-purified, freeze-dried.
    $428.00
  • raPOOL kit-2
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    siTOOLs Biotech

    raPOOL kit-2

    $714.00
    2 raPOOLs / target   2 raPOOLs, each containing 30 probes, are provided in this kit. Both raPOOLs contain different sets of probes specific to the target gene, differentiated by probe positions - odd-numbered (pool 1) and even-numbered probes...
    $714.00
  • raPOOL kit-3
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    siTOOLs Biotech

    raPOOL kit-3

    $921.00
    1 raPOOL / target+ 1 positive control raPOOL (MALAT1)+ 1 negative control raPOOL This kit contains 1 target-specific raPOOL, 1 positive control raPOOL against MALAT-1 that has previously been validated and a negative control raPOOL against LacZ to...
    $921.00
  • raPOOL kit-4
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    siTOOLs Biotech

    raPOOL kit-4

    $1,285.00
    2 raPOOLs / target+ 2 control raPOOLs This kit contains raPOOL 1 and 2 against the target RNA, and your selection of 2 control raPOOLs i.e. 2 pos. ctrl raPOOLs, 2 neg. ctrl raPOOLs or 1 positive ctrl raPOOL + 1 negative ctrl. raPOOL. Please indicate...
    $1,285.00
  • siPOOL- 10 Kit
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    siTOOLs Biotech

    siPOOL- 10 Kit

    $970.00
    10 nmol siPOOL10 nmol negative control siPOOL This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human. Amount provided: 10 nmol / siPOOL. PAGE-purified, freeze-dried.
    $970.00
  • siPOOL- 20 Kit
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    siTOOLs Biotech

    siPOOL- 20 Kit

    $1,506.00
    20 nmol siPOOL20 nmol negative control siPOOL This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human. Amount provided: 20 nmol / siPOOL. PAGE-purified, freeze-dried.
    $1,506.00
  • siPOOL- 5 Kit
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    siTOOLs Biotech

    siPOOL- 5 Kit

    $769.00
    5 nmol siPOOL5 nmol negative control siPOOL This kit contains the target-specific siPOOL and a negative control siPOOL against sequences not found in mouse, rat or human. Amount provided: 5 nmol / siPOOL. PAGE-purified, freeze-dried.
    $769.00