Affordable, Custom Ribosomal RNA Depletion for Any Species
Removing ribosomal RNAs (rRNAs) to allow sensitive detection of scientifically relevant RNAs by Next Generation Sequencing, is currently performed with costly kits limited to well-studied species.
riboPOOLs present an affordable and flexible solution that gives scientists absolute freedom to deplete rRNAs or other custom RNAs from any species.
Composed of high complexity pools of optimally-designed biotinylated DNA probes, riboPOOLs even outperformed Ribo-Zero (Illumina), depleting ~10% more rRNA while leaving other RNA intact.
Advantages of Our Technology
01 Highly efficient and specificHuman and mouse riboPOOLs depleted > 95% cytoplasmic and mitochondrial rRNA.
02 Any speciesDeplete rRNA from any species of your choice. Human, Mouse and Planarian in-stock. New species available on demand.
03 Low cost solutionA fraction of the price of existing solutions.
04 Deplete custom RNADeplete any RNA of your choice, e.g. globin from whole blood samples.
05 Applicable for non-polyadenylated RNAriboPOOLs do not depend on polyA- enrichment enabling detection of non-polyadenylated RNA.
06 Custom scales availableLarger scales available for custom application.
Specific, efficient rRNA depletion with riboPOOLs
Human riboPOOL depleted 98.6% of rRNA, compared to 80.6% by Ribo-Zero
Mouse riboPOOL depleted 96.4% of rRNA, compared to 86.1% by Ribo-Zero
Reproducible results with riboPOOLs
High reproducibility between biological replicates with human riboPOOLs
High reproducibility between biological replicates with mouse riboPOOls
HOW IT WORKS
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