Prepared from high grade porcine heparin using bacterial Heparinase and isolated by high resolution gel filtration.
General formula: ∆UA,2S - GlcNS,6S - (IdoA,2S – GlcNS,6S)n - IdoA,2S - GlcNS,6S
where 'n' is the number of disaccharide units
n = 0 in the dp4 (HO04) tetrasaccharide
n = 1 in the dp6 (HO06) hexasaccharide
n = 2 in the dp8 (HO08) octasaccharide, etc.
Uronic acid (∆UA) at the non-reducing end of the oligosaccharides has a C4-C5 double bond as a result of the endolytic action of bacterial heparinase. Although the main disaccharide unit in these products is IdoA,2S – GlcNS,6S (approx 75%) saccharides in each size class show some variation in sulfation.