Fractionated Heparan Sulphate Polymers

Fractionated Heparan Sulphate Polymers

Three distinct, highly purified heparan sulphate polymers isolated from porcine mucosa.

 

Three sulphated heparan sulphate polymers:

 

Heparan Sulphate fraction I: Mol wt approx. 40kDa

40 N-sulphate groups per 100 disaccharides

35 O-sulphate groups per 100 disaccharides

*Polymer sulphation (N- and O-sulphate groups) is 75 per 100 disaccharides

 

Heparan Sulphate fraction II: Mol wt. bimodal distribution 40kDa and 9kDa approx

55 N-sulphate groups per 100 disaccharides

70 O-sulphate groups per 100 disaccharides

*Polymer sulphation (N- and O-sulphate groups) is 125 per 100 disaccharides

 

Heparan Sulphate fraction III: Mol wt approx. 9kDa

65 N-sulphate groups per 100 disaccharides

110 O-sulphate groups per 100 disaccharides

*Polymer sulphation (N- and O-sulphate groups) is 175 per 100 disaccharides

 

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Heparan sulphate disaccharides

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