Chondroitin Sulphate D Oligosaccharides

Prepared from high quality, mixed isomer shark cartilage Chondroitin Sulfate D (CSD) by partial GAG-endolyase scission and isolated by high resolution gel filtration. The CSD Polymer used for preparation of the oligosaccharides contained 18% of the disulphated CSD disaccharide unit:
GlcA,2S – GalNAc,6S

General formula:

∆UA – (GalNAc,6S or 4S – GlcA +/- 2S)n – GalNAc,6S

where n is number of disaccharide units
n = 1 in a tetrasaccharide (dp4)
n = 2 in a hexasaccharide (dp6)
n = 3 1n an octasaccharide (dp8) etc…..

Uronic acid (∆UA) at the non-reducing ends of the oligosaccharides has a C4-C5 double bond as a result of endolytic scission.