6-O-Desulfated Heparin 2mg - DSH002/6

Approx 90% reduction in 6-O-sulphates and 25% loss of 2-O-sulphates.

These heparin products have been made from high quality heparin modified by standard chemical methods to selectively remove sulfate groups from C2 of Iduronate, (De2S Hep), C6 of glucosamine (De6SHep) or the N-sulfate of Glucosamine (DeNS Hep). The DeNS heparin contains the free amino group (NH+3); in DeNS/Ac Hep the free amino group has been modified by acetylation. This range of desulphated heparins is complemented by our series of sulphated K5 polysaccharides in which the internal uronate is glucuronic acid (GlcUA) in the native unmodified structure.